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Publications

Publications

Under preparation or review

 

Carmine Wang See, Jeun-Fai Lam, Jie Shen, Donghui Zhu*. Lubricative and immunomodulatory nanodiamonds for osteoarthritis treatment. Nature Biomedical Engineering, under preparation, 2024.

Carmine Wang See, Jeun-Fai Lam, Jie Shen, Donghui Zhu*. Dual functionality nanodiamonds targeting inflammation and friction for treatment of joint arthritis. ACS Nao, under preparation, 2024.

Juncen Zhou, Donghong Zhou, Sannakaisa Virtanen, Jie Shen, Lukasz Witek, Yunzhi Peter Yang, David Thanassi, Donghui Zhu*. Hybrid ZnO nanocoating on titanium implants: controlled drug release for enhanced antibacterial and osteogenic performance in infectious conditions. Small, under review, 2024.

Juncen Zhou, Negar Akrami, Jie Shen, Ben Zhang, Donghui Zhu*. Additively manufactured smart scaffolds for large bone defect healing. Chemical Engineering Journal, under review, 2024.

Juncen Zhou, Negar Akrami, Sai Sreenivasamurthy, Jie Shen, Donghui Zhu*. Revolutionizing ceramic bone cement with Zn particle doping: superior osteogenesis and bacteriostatic performance. Nature Chemical Engineering, under review, 2024.

Juncen Zhou, Donghui Zhu*. An injectable hydrogel for the treatment of osteoporotic nonunion bone fractures. Nature Chemical Engineering, under review, 2024.

Juncen Zhou, Rachel Brownlee, Tannous Henry, Eric J Rashba, Abhijeet Singh, Chunjiang Yu, Donghui Zhu*. Total bioabsorbable temporary epicardial pacing wire with excellent electrical performance and biocompatibility. Nature Electronics, under review, 2024.

Juncen Zhou, Sai Sreenivasamurthy, Donghui Zhu*. Woven bone organoids: advancing bone defect regeneration. Advanced Functional Materials, under review, 2024.

Juncen Zhou, Jiayi Zhou, Donghui Zhu*. Repurposing antidepression drug lithium for osteoporosis treatment. Nature Metabolism, under review, 2024.

 

Firoz Akhter, Asma Akhter, Zhen Zhao, Donghui Zhu*. Magnesium homeostasis dictates mitochondria-modulated neuroinflammation in Alzheimer’s disease. Nature Metabolism, under review, 2024.

 

Firoz Akhter, Asma Akhter, Zhen Zhao, Donghui Zhu*. Magnesium attenuates mitochondrial dysfunction and cognitive impairment in APOE ε4 mice. Cell Metabolism, under review, 2024.

 

Firoz Akhter, Asma Akhter, Zhen Zhao, Donghui Zhu*. APOE4 exacerbates glycative stress and STING-mediated neuroinflammation in Alzheimer’s disease. Neuron, under review, 2024.

 

Firoz Akhter, Asma Akhter, Zhen Zhao, Donghui Zhu*. AGE-mediated lipid droplets accumulation and neurovascular pathology in Alzheimer’s disease. Journal of Neuroscience, under review, 2024.

 

Firoz Akhter, Asma Akhter, Hillary Schiff, Arianna Maffei, Xiongwei Zhu, Justin Douglas, Zhen Zhao, Donghui Zhu*. Amyloid beta glycation leads to neuronal mitochondrial dysfunction and Alzheimer’s pathogenesis via VDAC1-dependent mtDNA efflux. Nature Metabolism, under review, 2024.

2024

Jingke Liu, Yingchao Su, Chase Linsley, Walaa Abd-Elaziem, Shuaihang Pan, Yuxin Zeng, Adam Gabriel, Narayanan Murali, Guan-Cheng Chen, Sarah Bialo, Andrew Jiang, Benjamin Wu, Donghui Zhu*, Xiaochun Li*. Nanoparticle-enabled Zn-0.1Mg Alloy with Long-term Stability, Refined degradation, and Favorable Biocompatibility for Biodegradable Implant Devices. ACS Applied Materials & Interfaces, in press, 2024.

Mariana Cabral, Ke Cheng, Donghui Zhu*. 3D Bioprinting of Organoids: past, present, and prospective. Tissue Engineering – Part A, in press, 2024.

 

Hyomin Jeong, Yingtian Pan, Firoz Akhter, Nora D. Volkow, Donghui Zhu*, Congwu Du*. Evidence of cortical vascular impairments in early stage of Alzheimer’s transgenic mice: optical imaging. Journal of Cerebral Blood Flow and Metabolism, in press, 2024.

 

Yuxin Zeng, Narayanan Murali, Carmine Wang See, Jinke Liu, Yitain Chi, Donghui Zhu, Chase Linsley, Benjamin Wu, Xiaochun Li. Effect of TiC Nanoparticles on Zn-Al-Cu System for Biodegradable Cardiovascular Stent Applications. ACS Biomaterials Science & Engineering, in press, 2024.

Liang Fang, Zhongting Liu, Cuicui Wang, Meng Shi, Yonghua He, Aiwu Lu, Xiaofei Li, Tiandao Li, Donghui Zhu, Jianjun Guan, Jie Shen. Vascular Restoration through Local Delivery of Angiogenic Factors Stimulates Bone Regeneration in Critical Size Defects. Bioactive Materials, in press, 2024.

2023

 

Juncen Zhou, Carmine Wang See, Sai Sreenivasamurthy, Donghui Zhu*. Customized additive manufacturing in bone scaffolds – the gateway to precise bone defect treatment. Research, 6, 0239, 2023.

 

Juncen Zhou, Elias Georgas, Yingchao Su, Jiayi Zhou, Nadja Kroger, Felix Benn, Alexander Kopp, Yi-Xian Qin, Donghui Zhu*. Evolution from Bioinert to Bioresorbable: In Vivo Comparative Study of Additively Manufactured Metal Bone Scaffolds. Advanced Science, 10 (26), 2302702, 2023.

 

Kakyung Kim, Yingchao Su, Allan Kucine, Ke Cheng, Donghui Zhu*. Guided bone regeneration using barrier membrane in dental application. ACS Biomaterials Science & Engineering, 9 (10), 5457-5478, 2023.

 

Yingchao Su, Matthew Cappock, Stephanie Dobres, Allan Kucine, Wayne Waltzer, Donghui Zhu*. Supplemental mineral ions for bone regeneration and osteoporosis treatment. Engineered Regeneration, 4:170, 2023.

 

Zhaojun Jia, Xiaoxue Xu, Donghui Zhu, Yufeng Zheng. Design, Printing, and Engineering of Regenerative Biomaterials for Personalized Bone Healthcare. Progress in Materials Science, 101072, 2023.

 

Yingchao Su, Jiayin Fu, Elias Georgas, Shaokang Du, Yi-Xian Qin, Yadong Wang, Yufeng Zheng, Donghui Zhu*. Blending with transition metals improves bioresorbable zinc as better medical implants. Bioactive Materials, 20: 243-258, 2023.

 

2022

 

L Yang, A Ball, J Liu, T Jain, YM Li, F Akhter, Donghui Zhu, J Wang. Cyclic microchip assay for measurement of hundreds of functional proteins in single neurons. Nature Communications, 13 (1), 1-11, 2022.

 

Sai Sreenivasamurthy, Mahek Laul, Tiffany Kim, Nan Zhao, Donghui Zhu*. Current progress of cerebral organoids for modeling Alzheimer’s disease origins and mechanisms. Bioengineering & Translational Medicine, e10378, 2022.

 

Jimiao Jianga, Hua Huanga, Jialin Niua, Donghui Zhu, Guangyin Yuan. Fabrication and characterization of biodegradable Zn-Cu-Mn alloy micro-tubes and vascular stents: microstructure, texture and mechanical properties. Acta Biomaterialia, 151, 647-660, 2022.

 

Sai A. Sreenivasamurthy, Firoz Akhter, Asma Akhter, Yingchao Su, Donghui Zhu*. Cellular mechanisms of biodegradable zinc and magnesium materials on promoting angiogenesis. Biomaterials Advances, 139, 213023, 2022.

 

Alicia Persaud, Alexander Maus, Lia Strait, Donghui Zhu*. 3D Bioprinting with Live Cell. Engineered Regeneration, 3(3): 292-309, 2022.

 

C Chen, J Niu, H Huang, Donghui Zhu, JF Nie, G Yuan. Basal-plane stacking fault energies of biodegradable Zn-based alloys: A first-principles study of alloying effects. Materials Letters, 309, 131413, 2022.

 

Stephanie Dobres, Giridhar Mula, Jonathan Sauer, Donghui Zhu*. Applications of 3D Printed Chimeric DNA Biomaterials. Engineered Regeneration, 3 (1): 13-23, 2022.

 

Michael Ly, Shayne Hays, Sarah Spinelli, Donghui Zhu*. 3D Printing of Ceramic Biomaterials. Engineered Regeneration, 3 (1): 41-52, 2022.

 

Yingchao Su, Jiayin Fu, Wonsae Lee, Shaokang Du, Yi-Xian Qin, Yufeng Zheng, Yadong Wang, Donghui Zhu*. Improved mechanical, degradation, and biological performances of Zn-Fe alloys as bioresorbable implants. Bioactive Materials, 17: 334-343, 2022.

 

Yingchao Su, Jiayin Fu, Elias Georgas, Yi-Xian Qin, Yufeng Zheng, Yadong Wang, Donghui Zhu*. Biodegradable Zn-Sr alloys with enhanced mechanical and biocompatibility for biomedical applications. Smart Materials in Medicine, 3: 117-127, 2022.

 

2021

K Chua, I Khan, R Malhotra, Donghui Zhu*. Additive Manufacturing and 3D Printing of Metallic Biomaterials. Engineered Regeneration, 2: 288-299, 2021.

 

Donghui Zhu*, Montagne A, Zhao Z. Alzheimer’s Pathogenic Mechanisms and underlying Sex Difference. Cellular and Molecular Life Sciences, 1-14, 2021.

 

Fnu Firoz Akhter, Alicia Persaud, Younis Zaokari, Zhen Zhao, Donghui Zhu*. Vascular Dementia and Underlying Sex Differences. Frontiers in Aging Neuroscience, 13:720715, 2021

 

Chen C, S Fan, J Niu, H Huang, Z Jin, L Kong, D Zhu, G Yuan. Materials & Design, 109676, 2021.

 

Maus A, L Strait, D Zhu*. Nanoparticles as delivery vehicles for antiviral therapeutic drugs. Engineered Regeneration, 2:31-46, 2021.

 

Ben Zhang, Juncen Zhou, Yingchao Su, Yufeng Zheng, Donghui Zhu*. Towards a Better Regeneration through Scaffold-guided Immunomodulation: Harnessing the Innate and Adaptive Responses.  Advanced Science, 2100446, 2021.

 

Irsalan Cockerill, Carmine Wang See, Marcus Young, Yadong Wang, Donghui Zhu*.  Designing Better Cardiovascular Stent Materials – A Learning Curve. Advanced Functional Materials, 31 (1): 2005361, 2021.

 

2020 and before

Yong Wu, Qiongyu Hao, Pranabananda Dutta, Piwen Wang, Seyung Chung, Qun Li, Kun Wang, Jieqing Li, Wei Cao, Wenhong Deng, Qing Geng, Katrina Schrode, Magda Shaheen, Ke Wu, Donghui Zhu, et al. Comp34 displays potent preclinical antitumor efficacy in triple-negative breast cancer via inhibition of NUDT3-AS4, a novel oncogenic long non-coding RNA.  Cell Death & Disease, 11: 1-18, 2020.

 

Tiffany Kim, Carmine Wang See, Xiaochun Li, Donghui Zhu*.  Orthopedic Implants and Devices for Bone Fractures and Defects: Past, Present and Perspective.  Engineered Regeneration, 1: 6-18, 2020.

 

Carmine Wang See, Tiffany Kim, Donghui Zhu*. Hernia Mesh and Hernia Repair: A Review. Engineered Regeneration, 1: 19-33, 2020.

 

Marina Safonov, Jing You, Jihyung Lee, Vladimir L. Safonov, Diana Berman, Donghui Zhu*. Hydrogen generating patch improves skin cell viability, migration activity, and collagen expression. Engineered Regeneration, 1: 1-5, 2020.

 

Irsalan Cockerill, Yingchao Su, Ji Hyung Lee, Diana Berman, Yufeng Zheng, Marcus Young, and Donghui Zhu*.  Micro-/Nano-Topography on Bioresorbable Zinc Dictates Cytocompatibility, Bone Cell Differentiation, and Macrophage Polarization. Nano Letters, 20: 4594-4602, 2020.

 

Irsalan Cockerill, Yingchao Su, Yufeng Zheng, Yi-Xian Qin, Marcus Young, and Donghui Zhu*.  Porous Zinc Scaffolds for Bone Tissue Engineering Applications: A Novel Additive Manufacturing and Casting Approach. Materials Science & Engineering C, 110: 110738, 2020.

 

Wei Yuan, Dandan Xia, Yufeng Zheng, Xiangmei Liu, Shuilin Wu, Bo Li, Yong Han, Zhaojun Jia, Donghui Zhu, et al. Controllable biodegradation and enhanced osseointegration of ZrO2 nanofilm coated Zn-Li alloy: in vitro and in vivo studies.  Acta Biomaterialia, 105: 290-303, 2020.

 

Hongtao Yang, Bo Jia, Zechuan Zhang, Xinhua Qu, Guannan Li, Wenjiao Lin, Donghui Zhu, Kerong Dai, Yufeng Zheng. Alloying design of biodegradable zinc as promising bone implants for load-bearing applications. Nature Communications, 11 (1): 1-16, 2020.

 

Jiayin Fu, Yingchao Su, Yi-Xia Qin, Yufeng Zheng, Yadong Wang, Donghui Zhu*.  Evolution of metallic cardiovascular stent materials: a comparative study among stainless steel, magnesium and zinc. Biomaterials, 230: 119641, 2020.

 

Irsalan Cockerill, Yingchao Su, Reid Bitten, Benjamin Cloarec, Samir Aouadi, Donghui Zhu*, and Marcus Young. Salt Preform Texturing of Bioresorbable Zn Substrates for Bone-implant Applications. JOM, 72: 1902, 2020.

 

Asghar Shirani, Qichan Hu, Diana Berman, and Donghui Zhu*. Combined tribological and bactericidal effect of nanodiamonds as potential lubricant for artificial joints.  ACS Applied Materials and Interfaces, 11: 43500, 2019.

 

Hongtao Yang, Donghui Zhu, Yufeng Zheng. Challenges of zinc and its alloys as biodegradable metals: perspective from biomechanical compatibility. Acta Biomaterialia, 97: 23-45, 2019.

 

Joy-Anne N. Oliver, Yingchao Su, Xiaonan Lu, Po-Hsuen Kuo, Jincheng Du, and Donghui Zhu*. Bioactive glass coatings on metallic implants.  Bioactive Materials, 4: 261-270, 2019.

 

Donghui Zhu*, Jing You, Nan Zhao, and Huaxi Xu. Magnesium controls endothelial barrier functions through TRPM7, MagT1 and S1P1. Advanced Science, 6(18): 1901166, 2019.

 

Qun Li, Qiongyu Hao, Wei Cao, Jieqing Li, Ke Wu, Yahya Elshimali, Donghui Zhu, et al. PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response.  Science Advances, 5(10): eaaw8417, 2019.

 

Yang Liu, Yufeng Zheng, Xie-Hui Chen, Jian-An Yang, Haobo Pan, Dafu Chen, Luning Wang, Jialiang Zhang, Donghui Zhu, et al. Fundamental theory of biodegradable metals – definition, criteria, and design.  Advanced Functional Materials, 29: 1805402, 2019.

 

Yingchao Su, Hongtao Yang, Julia Gao, Yi-Xia Qin, Yufeng Zheng, Donghui Zhu*.  Interfacial zinc phosphate is the key controlling biocompatibility of Zn implants. Advanced Science, 6(14): 1900112, 2019.

 

Yingchao Su, Kai Wang, Julia Gao, Yong Yang, Yi-Xia Qin, Yufeng Zheng, Donghui Zhu*.  Engineering a zinc phosphate coating on zinc for enhanced biocompatibility and antibacterial property. Acta Biomaterialia, 98: 174-185, 2019.

 

Yingchao Su, Lingqian Chang, Irsalan Cockerill, Yufeng Zheng, Yi-Xian Qin, Donghui Zhu*. Biofunctionalization of metallic implants by calcium phosphate coatings, Bioactive Materials, 4: 196, 2019.

 

Donghui Zhu*, Irsalan Cockerill, Zhaoxiang Zhang, Jiayin Fu, Kee-Won Lee, Jun Ma, Yingchao Su, Chuka Okpokwasili, Liping Tang, Yufeng Zheng, Yi-Xia Qin and Yadong Wang.  Mechanical Strength, Biodegradation, and In Vitro and In Vivo Biocompatibility of Zn Biomaterials. ACS Applied Materials and Interfaces, 11: 6809, 2019.

 

Wei Yuan, Bo Li, Dafu Chen, Donghui Zhu, Yong Han, Yufeng Zheng. Formation mechanism, corrosion behavior and cytocompatibility of microarc oxidation coating on absorbable high-purity zinc.  ACS Biomaterials Science & Engineering, 5: 487, 2019.

 

Yingchao Su, Irsalan Cockerill, Yadong Wang, Yi-Xian Qin, Lingqian Chang, Yufeng Zheng, Donghui Zhu*. Zinc-Based Biomaterials for Regeneration and Therapy.  Trends in Biotechnology, 37: 428-441, 2019.

 

Ke Wu, Xiaoting Yu, Zhimin Huang, Donghui Zhu, et al. Targeting of PP2Cδ by a small molecule C23 inhibits high glucose-induced breast cancer progression in vivo, Antioxidants and Redox Signaling, 30: 1983, 2019.

 

Hongtao Yang, Xinhua Qu, Wenjiao Lin, Dafu Chen, Donghui Zhu, Kerong Dai, Yufeng Zheng. Enhanced osseointegration of Zn-Mg composites by tuning the release of Zn ions with sacrificial Mg rich anode design.   ACS Biomaterials Science & Engineering, 5: 453, 2019.

 

Yunting Guo, Yingchao Su, Siqi Jia, Guixun Sun, Rui Gu, Donghui Zhu, Guangyu Li, Jianshe Lian. Hydroxyapatite/titania composite coatings on biodegradable magnesium alloy for enhanced corrosion resistance, cytocompatibility and antibacterial properties. Journal of The Electrochemical Society, 165: C962, 2018

 

Bai W, Kuang T, Chitrakar C, Yang R, Li S, Donghui Zhu, Chang L. Patchable micro/nanodevices interacting with skin. Biosensors and Bioelectronics, 122: 189, 2018

 

Hongtao Yang, Xinhua Qu, W Lin, Cong Wang, Donghui Zhu, Kerong Dai, Yufeng Zheng. In vitro and in vivo studies on zinc-hydroxyapatite composites as novel biodegradable metal matrix composite for orthopedic applications.  Acta Biomaterialia, 71: 200, 2018.

 

Donghui Zhu*, Yingchao Su, Bingmei Fu, and Huaxi Xu. Magnesium reduces BBB permeability and regulates amyloid-β transcytosis.  Molecular Neurobiology, 55: 7118, 2018.

 

Donghui Zhu*, Yingchao Su, Yufeng Zheng, et al. Zinc regulates vascular endothelial activities through zinc-sensing receptor ZnR/GPR39.  American Journal of Physiology-Cell Physiology, 314: C404, 2018.

 

Wu Y, Dong Y, Duan S, Donghui Zhu, Deng L. Metabolic Syndrome, Inflammation, and Cancer. Mediators Inflammation. 2017:8259356, 2017.

 

Yingchao Su, Cheng Luo, Zhihui Zhang, Hendra Hermawan, Donghui Zhu, Jubin Huang, Guangyu Li, Luquan Ren. Bioinspired surface functionalization of metallic biomaterials, Journal of the Mechanical Behavior of Biomedical Materials, 77: 90, 2017.

 

Donghui Zhu*, Yingchao Su, Marcus Young, Jun Ma, Yufeng Zheng, and Liping Tang. Biological responses and mechanisms of human bone marrow mesenchymal stem cells to Zn and Mg biomaterials.  ACS Applied Materials and Interfaces, 9: 27453, 2017.

 

Hongtao Yang, Cong Wang, Chaoqiang Liu, Houwen Chen, Yifan Wu, Jintao Han, Zichang Jia, Wenjiao Lin, Deyuan Zhang, Wenting Li, Wei Yuan, Hui Guo, Huafang Li, Guangxin Yang, Deling Kong, Donghui Zhu, Kazuki Takashima, Liqun Ruan, Jianfeng Nie, Xuan Li and Yufeng Zheng. Evolution of degradation mechanism of pure zinc stent in the one-year study of rabbit abdominal aorta model.  Biomaterials, 145: 92, 2017.

 

Ma J, Zhao N, Donghui Zhu*.  Bioabsorbable zinc ion induced biphasic cellular responses in vascular smooth muscle cells. Scientific Reports, 6: 26661, 2016.

 

Ma J, Zhao N, Donghui Zhu*.  Biphasic responses of human vascular smooth muscle cells to magnesium ion. Journal of Biomedical Materials Research: Part A, 104A: 347, 2016.

 

Ma J, Betts L, Zhao N, Donghui Zhu*. Bio-adaption between the Mg alloy stent and the blood vessel. Journal of Materials Science & Technology, 32: 815, 2016.

 

Ma J, Donghui Zhu*, A comparative study of in vitro biocompatibility of Zn and AZ31 for cardiovascular stent application, Frontiers in Bioengineering and Biotechnology, 4, 2016.

 

Ma J, Zhao N, Donghui Zhu*.  Endothelial cellular responses to biodegradable metal zinc. ACS Biomaterials Science & Engineering, 1:1174, 2015.

 

Ma J, Zhao N, Donghui Zhu*.  Sirolimus-eluting dextran and polyglutamic acid hybrid coatings on AZ31 for stent applications. Journal of Biomaterial Applications, 30:579, 2015.

 

Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Donghui Zhu, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance, Nature Neuroscience, 18:978, 2015.

 

Donghui Zhu, Bungart B, Yang X, Zhumadilov Z, Lee J, Askarova S.  Role of membrane biophysics in Alzheimer’s disease, Frontiers in Neuroscience, 9:186, 2015.

 

Zhao N, Donghui Zhu*. Endothelial responses of magnesium and other alloying elements in magnesium-based stent materials. Metallomics, 7:113, 2015.

 

Zhao N, Donghui Zhu*. Collagen self-assembly on orthopedic magnesium biomaterials surface and subsequent bone cell attachment. PLoS One, 9:e110420, 2014.

 

Ma J, Thompson M, Zhao N, Donghui Zhu*. Similarity and difference in coatings for Mg-based stent and orthopaedic implants, Journal of Orthopaedic Translation, 2: 118, 2014.

 

Zhao N, Watson N, Chen J, Xu Z, Waterman J, Sankar J, Donghui Zhu*.  Biocompatibility and Endothelialization of Novel Magnesium-Rare earth Alloys for Improved Stent Applications.  PLoS One, 9: e98674, 2014.

 

Zhao N, Workman B, Donghui Zhu*. Endothelialization of novel magnesium-rare earth alloys with fluoride and collagen coatings, International Journal of Molecular Sciences, 15: 5263, 2014.

 

Zhao N, Ma J, Donghui Zhu*, In vitro biocompatibility of novel magnesium-rare earth based stent materials, European Cells and Materials 28(3): 61, 2014.

 

Zhao N, Donghui Zhu*, Endothelial growth on fluoride and collagen coated magnesium alloys, European Cells and Materials 28(3): 59, 2014.

 

Ma J, Zhao N, Donghui Zhu*, Novel magnesium-based stent biomaterials with anti-corrosion and drug-eluting coatings, European Cells and Materials 28(3): 68, 2014

 

Zhao N, Donghui Zhu*.  Bioscaffolds Development for Small-Diameter Vascular
Grafts, International Journal of Biomedical Engineering and Technology, 12: 113, 2013.

 

Zhao N, Donghui Zhu*. Application of Mg-based alloys for cardiovascular stent, International Journal of Biomedical Engineering and Technology, 12: 382, 2013.

 

Donghui Zhu, Wang Y, Bell R, et al. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the Tyro3-dependent cross-activation of sphingosine 1-phosphate receptor, Blood, 115, 4963, 2010.

 

Donghui Zhu*, Hu C, Sheng W, et al. NADPH oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2.  Biochemical Journal, 421: 201-210, 2009.

 

Hicks JB, Lai Y, Sheng W, Donghui Zhu, et al. Amyloid-beta peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A2.  BBA-Biomembranes, 1178: 2512, 2008.

 

Donghui Zhu, Haidekker MA, Lee JS, et al. Application of Molecular Rotors to the Determination of the Molecular Weight-Dependence of Viscosity in Polymer Melts. Macromolecules, 40: 7730, 2007.

 

Donghui Zhu.  Mathematical modeling of blood coagulation cascade: kinetics of intrinsic and extrinsic pathways in normal and deficient conditions. Blood Coagulation and Fibrinolysis, 18: 637, 2007.

 

Donghui Zhu, Lai Y, Shelat PB, et al. Phospholipases A2 mediate Alzheimer’s Aβ-induced mitochondrial dysfunction.  Journal of Neuroscience, 26: 11111, 2006.

 

Donghui Zhu, Lennon SP, Peters MH, et al. Brownian diffusion and surface kinetics of liposome and viral particle uptake by human lung cancer cells in-vitro. Annals of Biomedical Engineering, 34: 1573, 2006.

 

Donghui Zhu, Sun GY, Lee JCM. Oxidative Stress Alters Membrane Microdomains in Glial Cells. Biophysical Journal, 88: 595A, 2005.

 

Donghui Zhu, Tan KS, Zhang X, et al. Hydrogen peroxide alters membrane and cytoskeleton properties and enhances intercellular connections in astrocytes. Journal of Cell Science, 118: 3695, 2005. 

 

Wei D, Li J, Donghui Zhu, et al. Synthesis and purification of a novel DNA intercalator-oligonucleotide conjugate. International Journal of Biochromatography, 6: 87, 2001.

 

Li J, Wei D, Donghui Zhu, et al. Inhibition of multidrug resistance in human tumor cell by naphthyl imide-conjugated anti-sense oligonucleotide. Chinese Journal of Cancer, 20: 373, 2001.

 

Qian X, Wei D, Donghui Zhu, et al. Interaction of naphthyl heterocycles with DNA: effects of thiono and thio groups. Journal of the Chemical Society-Perkin Transactions 2, 4: 715, 2000. 

 

Li J, Wei D, Donghui Zhu, and Zhang Y. Synthesis of oligonucleotide-DNA Intercalator Conjugates. Chinese Journal of Pharmaceuticals, 31: 559, 2000.

 

Huang T, Donghui Zhu, et al. General synthesis of thioxo-1, 8-naphthalimides via thioxo-1, 8-naphthalic anhydrides. Synthesis, 7: 1109, 1999.

 

Donghui Zhu, and Wei D.  Study of second generation of anti-sense oligonucleotide.  Progress in Pharmaceuticals Sciences, 23: 9, 1999.

The Zhu Lab 

Department of Biomedical Engineering

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